Anti-Browning Effect of 2-Mercaptobenzo[<i>d</i>]imidazole Analogs with Antioxidant Activity on Freshly-Cut Apple Slices and Their Highly Potent Tyrosinase Inhibitory Activity

• Váldodahkkit: Jieun Lee (Dahkki), Hye Soo Park (Dahkki), Hee Jin Jung (Dahkki), Yu Jung Park (Dahkki), Min Kyung Kang (Dahkki), Hye Jin Kim (Dahkki), Dahye Yoon (Dahkki), Sultan Ullah (Dahkki), Dongwan Kang (Dahkki), Yujin Park (Dahkki), Pusoon Chun (Dahkki), Hae Young Chung (Dahkki), Hyung Ryong Moon (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: MDPI AG, 2023-09-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Ten 2-mercaptobenzimidazole (2-MBI) analogs were synthesized as potential tyrosinase inhibitors because mercapto-containing compounds can bind to copper ions at the active site of tyrosinase to inhibit enzyme activity. Nine 2-MBI analogs showed sub-micromolar IC₅₀ values for m...