Development studies of captopril certified reference material

• Main Authors: Raquel Nogueira (Author), Eliane Cristina Pires do Rego (Author), Marcus Vinicius Barreto Sousa (Author), Wagner Wollinger (Author), Thaís Elias da Silva (Author), Gabriela Fernandes Moreira (Author), Juliano Smanioto Barin (Author), Luciane Varini Laporta (Author), Márcia Foster Mesko (Author), Celso Figueiredo Bittencourt (Author), Janaína Marques Rodrigues (Author), Valnei Smarçaro da Cunha (Author)
• Format: Book
• Published: Universidade de São Paulo, 2011-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This paper describes the studies performed with the candidate Certified Reference Material (CRM) of captopril, the first CRM of an active pharmaceutical ingredient (API) in Brazil, including determination of impurities (organic, inorganic and volatiles), homogeneity testing, short- and long-term sta...