Differential Activation of Glioprotective Intracellular Signaling Pathways in Primary Optic Nerve Head Astrocytes after Treatment with Different Classes of Antioxidants

• Main Authors: Anita K. Ghosh (Author), Vidhya R. Rao (Author), Victoria J. Wisniewski (Author), Alexandra D. Zigrossi (Author), Jamie Floss (Author), Peter Koulen (Author), Evan B Stubbs (Author), Simon Kaja (Author)
• Format: Book
• Published: MDPI AG, 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Optic nerve head astrocytes are the specialized glia cells that provide structural and trophic support to the optic nerve head. In response to cellular injury, optic nerve head astrocytes undergo reactive astrocytosis, the process of cellular activation associated with cytoskeletal remodeling, incre...