Recurrence of the oxazole motif in tubulin colchicine site inhibitors with anti-tumor activity

• Main Authors: Marilia Barreca (Author), Virginia Spanò (Author), Maria Valeria Raimondi (Author), Chiara Tarantelli (Author), Filippo Spriano (Author), Francesco Bertoni (Author), Paola Barraja (Author), Alessandra Montalbano (Author)
• Format: Book
• Published: Elsevier, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Because of its wide spectrum of targets and biological activities, the oxazole ring is a valuable heterocyclic scaffold in the design of new therapeutic agents with anticancer, antiviral, antibacterial, anti-inflammatory, neuroprotective, antidiabetic and antidepressant properties. The presence of t...