Triazoloquinoxalines-based DNA intercalators-Topo II inhibitors: design, synthesis, docking, ADMET and anti-proliferative evaluations

Sixteen [1, 2, 4]triazolo[4,3-a]quinoxalines as DNA intercalators-Topo II inhibitors have been prepared and their anticancer actions evaluated towards three cancer cell lines. The new compounds affected on high percentage of MCF-7. Derivatives 7e, 7c and 7b exhibited the highest anticancer activitie...

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Main Authors: Alaa Elwan (Author), Helmy Sakr (Author), Abdel-Ghany (Author), Ahmed El-morsy (Author), Mohamed A. Abdelgawad (Author), Mohammed M. Ghoneim (Author), Mohamed El-Sherbiny (Author), Khaled El-Adl (Author)
Format: Book
Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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