A review of dupilumab in the treatment of atopic diseases

• Main Authors: Quinn Thibodeaux (Author), Mary Patricia Smith (Author), Karen Ly (Author), Kristen Beck (Author), Wilson Liao (Author), Tina Bhutani (Author)
• Format: Book
• Published: Taylor & Francis Group, 2019-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dupilumab is a fully human monoclonal IgG4 antibody directed against the alpha subunit of the IL-4 receptor and prevents the signaling of IL-4 and IL-13, two type 2 cytokines known to be important drivers of atopic diseases. In March of 2017, the United States Food and Drug Administration (FDA) appr...