Notoginsenoside R1 improves intestinal microvascular functioning in sepsis by targeting Drp1-mediated mitochondrial quality imbalance

• Main Authors: Dongyao Hou (Author), Ruixue Liu (Author), Shuai Hao (Author), Yong Dou (Author), Guizhen Chen (Author), Liangming Liu (Author), Tao Li (Author), Yunxing Cao (Author), He Huang (Author), Chenyang Duan (Author)
• Format: Book
• Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

AbstractContext Sepsis can result in critical organ failure, and notoginsenoside R1 (NGR1) offers mitochondrial protection.Objective To determine whether NGR1 improves organ function and prognosis after sepsis by protecting mitochondrial quality.Materials and methods A sepsis model was established i...