ephrin-B2 promotes nociceptive plasticity and hyperalgesic priming through EphB2-MNK-eIF4E signaling in both mice and humans

• 主要な著者: Eric T. David (著者), Muhammad Saad Yousuf (著者), Hao-Ruei Mei (著者), Ashita Jain (著者), Sharada Krishnagiri (著者), Hajira Elahi (著者), Rupali Venkatesan (著者), Kolluru D. Srikanth (著者), Gregory Dussor (著者), Matthew B. Dalva (著者), Theodore J. Price (著者)
• フォーマット: 図書
• 出版事項: Elsevier, 2024-08-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Ephrin-B-EphB signaling can promote pain through ligand-receptor interactions between peripheral cells, like immune cells expressing ephrin-Bs, and EphB receptors expressed by DRG neurons. Previous studies have shown increased ephrin-B2 expression in peripheral tissues like synovium of rheumatoid an...