Warfarin Anticoagulation Therapy in Caribbean Hispanics of Puerto Rico: A Candidate Gene Association Study

• मुख्य लेखकों: Karla Claudio-Campos (लेखक), Aurora Labastida (लेखक), Alga Ramos (लेखक), Andrea Gaedigk (लेखक), Jessicca Renta-Torres (लेखक), Dariana Padilla (लेखक), Giselle Rivera-Miranda (लेखक), Stuart A. Scott (लेखक), Gualberto Ruaño (लेखक), Carmen L. Cadilla (लेखक), Jorge Duconge-Soler (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2017-06-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Existing algorithms account for ~50% of observed variance in warfarin dose requirements after including common polymorphisms. However, they do not perform as well in populations other than Caucasians, in part because some ethno-specific genetic variants are overlooked. The objective of the present s...