Garcinol Attenuates Lipoprotein(a)-Induced Oxidative Stress and Inflammatory Cytokine Production in Ventricular Cardiomyocyte through α7-Nicotinic Acetylcholine Receptor-Mediated Inhibition of the p38 MAPK and NF-κB Signaling Pathways

• मुख्य लेखकों: Nen-Chung Chang (लेखक), Chi-Tai Yeh (लेखक), Yen-Kuang Lin (लेखक), Kuang-Tai Kuo (लेखक), Iat-Hang Fong (लेखक), Nicholas G. Kounis (लेखक), Patrick Hu (लेखक), Ming-Yow Hung (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2021-03-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Garcinol, a nicotinic acetylcholine receptor (nAChR) antagonist, has recently been established as an anti-inflammation agent. However, the molecular mechanism by which garcinol suppresses inflammation in the context of acute myocardial infarction (AMI) remains unclear. <b>Hypothesis:</b>...