An analytical method for assessing stage-specific drug activity in Plasmodium vivax malaria: implications for ex vivo drug susceptibility testing.

• Main Authors: Douglas H Kerlin (Author), Kane Boyce (Author), Jutta Marfurt (Author), Julie A Simpson (Author), Enny Kenangalem (Author), Qin Cheng (Author), Ric N Price (Author), Michelle L Gatton (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The emergence of highly chloroquine (CQ) resistant P. vivax in Southeast Asia has created an urgent need for an improved understanding of the mechanisms of drug resistance in these parasites, the development of robust tools for defining the spread of resistance, and the discovery of new antimalarial...