Empagliflozin Alleviates Hepatic Steatosis by Activating the AMPK-TET2-Autophagy Pathway in vivo and in vitro

• Main Authors: Ting Li (Author), Ting Fang (Author), Linxin Xu (Author), Xiangyang Liu (Author), Xiaoyu Li (Author), Mei Xue (Author), Xiaochen Yu (Author), Bei Sun (Author), Liming Chen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Metabolic associated fatty liver disease (MAFLD), characterized by hepatic lipid accumulation and fatty degeneration, is intertwined with obesity and type 2 diabetes mellitus (T2DM). Empagliflozin is a sodium-glucose cotransporter-2 inhibitor that effectively lowers blood glucose, but it...