Meldonium Inhibits Cell Motility and Wound-Healing in Trabecular Meshwork Cells and Scleral Fibroblasts: Possible Applications in Glaucoma

• Main Authors: Cristina Minnelli (Author), Francesco Piva (Author), Monia Cecati (Author), Tatiana Armeni (Author), Giovanna Mobbili (Author), Roberta Galeazzi (Author), Alberto Melecchi (Author), Martina Cristaldi (Author), Roberta Corsaro (Author), Dario Rusciano (Author)
• Format: Book
• Published: MDPI AG, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Meldonium (MID) is a synthetic drug designed to decrease the availability of L-carnitine-a main player in mitochondrial energy generation-thus modulating the cell pathways of energy metabolism. Its clinical effects are mostly evident in blood vessels during ischemic events, when the hyperproduction...