Tetramethylpyrazine nitrone activates hypoxia-inducible factor and regulates iron homeostasis to improve renal anemia

• Main Authors: Yun Cen (Author), Peile Wang (Author), Fangfang Gao (Author), Mei Jing (Author), Zaijun Zhang (Author), Peng Yi (Author), Gaoxiao Zhang (Author), Yewei Sun (Author), Yuqiang Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Renal anemia is one of the most common complications of chronic kidney disease and diabetic kidney disease. Despite the progress made in recent years, there is still an urgent unmet clinical need for renal anemia treatment. In this research, we investigated the efficacy and mechanism of action of th...