Formononetin Activates the Nrf2/ARE Signaling Pathway Via Sirt1 to Improve Diabetic Renal Fibrosis

• Main Authors: Kai Zhuang (Author), Xiyu Jiang (Author), Renbin Liu (Author), Cunsi Ye (Author), Yumei Wang (Author), Yunhan Wang (Author), Shijian Quan (Author), Heqing Huang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Oxidative stress is the main factor responsible for the induction of diabetic renal fibrosis. Thus, improving the state of oxidative stress can effectively prevent the further deterioration of diabetic nephropathy (DN). Previous research has shown that formononetin (FMN), a flavonoid with significan...