Inhibitory Mechanism of Monensin on High K+-Induced Contraction in Guniea-Pig Urinary Bladder

• Main Authors: Takeharu Kaneda (Author), Mayumi Takeuchi (Author), Kazumasa Shimizu (Author), Norimoto Urakawa (Author), Shinjiro Nakajyo (Author), Mariko Mochizuki-Kobayashi (Author), Fukiko Ueda (Author), Ryo Hondo (Author)
• Format: Book
• Published: Elsevier, 2006-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract.: In this study, we examined the inhibitory mechanism of monensin on high K+-induced contraction in guinea-pig urinary bladder. The relaxant effect of monensin (0.001 - 10 µM) was more potent than those of NaCN (100 µM - 1 mM) and forskolin (3 - 10 µM). Monensin (0.1 µM), NaCN (300 µM), or...