Chaenomelis fructus inhibits osteoclast differentiation by suppressing NFATc1 expression and prevents ovariectomy-induced osteoporosis

• Main Authors: Minsun Kim (Author), Ho-Seok Kim (Author), Jae-Hyun Kim (Author), Eun-Young Kim (Author), Bina Lee (Author), Sung Yub Lee (Author), Jae-Yun Jun (Author), Min Beom Kim (Author), Youngjoo Sohn (Author), Hyuk-Sang Jung (Author)
• Format: Book
• Published: BMC, 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Osteoporosis is related to the number and activity of osteoclasts. The goal of the present study was to demonstrate the effect of Chaenomelis Fructus (CF) on osteoclastogenesis and its mechanism of bone loss prevention in an OVX-induced osteoporosis model. Methods Osteoclasts wer...