Intrauterine Low-Protein Diet Exacerbates Abnormal Development of the Urinary System in Gen1-Mutant Mice

• Main Authors: Minghui Yu (Author), Yaxin Li (Author), Lihong Tan (Author), Jing Chen (Author), Yihui Zhai (Author), Jia Rao (Author), Xiaoyan Fang (Author), Jialu Liu (Author), Jiaojia Liu (Author), Xiaohui Wu (Author), Hong Xu (Author), Qian Shen (Author)
• Format: Book
• Published: Karger Publishers, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Gen1 mutation can cause various phenotypes of congenital anomaly of the kidney and urinary tract (CAKUT). An intrauterine low-protein isocaloric diet can also cause CAKUT phenotypes in offspring. However, single factors such as gene mutation or abnormal environmental factor during pregna...