Inhibition of HDAC6 Attenuates Diabetes-Induced Retinal Redox Imbalance and Microangiopathy

Inhibition of HDAC6 Attenuates Diabetes-Induced Retinal Redox Imbalance and Microangiopathy

We investigated the contributing role of the histone deacetylase 6 (HDAC6) to the early stages of diabetic retinopathy (DR). Furthermore, we examined the mechanism of action of HDAC6 in human retinal endothelial cells (HuREC) exposed to glucidic stress. Streptozotocin-induced diabetic rats (STZ-rats...

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Main Authors: Hossameldin Abouhish (Author), Menaka C. Thounaojam (Author), Ravirajsinh N. Jadeja (Author), Diana R. Gutsaeva (Author), Folami L. Powell (Author), Mohamed Khriza (Author), Pamela M. Martin (Author), Manuela Bartoli (Author)
Format: Book
Published: MDPI AG, 2020-07-01T00:00:00Z.
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