Western Diet Causes Obesity-Induced Nonalcoholic Fatty Liver Disease Development by Differentially Compromising the Autophagic Response

• Main Authors: Ines C. M. Simoes (Author), Agnieszka Karkucinska-Wieckowska (Author), Justyna Janikiewicz (Author), Sylwia Szymanska (Author), Maciej Pronicki (Author), Pawel Dobrzyn (Author), Michal Dabrowski (Author), Agnieszka Dobrzyn (Author), Paulo J. Oliveira (Author), Hans Zischka (Author), Yaiza Potes (Author), Mariusz R. Wieckowski (Author)
• Format: Book
• Published: MDPI AG, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nonalcoholic fatty liver disease (NAFLD) is characterized by the development of steatosis, which can ultimately compromise liver function. Mitochondria are key players in obesity-induced metabolic disorders; however, the distinct role of hypercaloric diet constituents in hepatic cellular oxidative s...