Tumour necrosis factor (TNF) and interleukin-1 (IL-1) induce muscle proteolysis through different mechanisms

Tumour necrosis factor (TNF) and interleukin-1 (IL-1) induce muscle proteolysis through different mechanisms

The purpose of this study was to test the hypothesis that muscle proteolysis induced by TNF or IL-1 is mediated by glucocorticoids. Rats were treated with 300 μg kg−1 of recombinant human preparations of IL-1α (rIL-1α) or TNFα (rTNFα) divided into three equal intraperitoneal doses given over 16 h. T...

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Main Authors: Oded Zamir (Author), Per-Olof Hasselgren (Author), Takashi Higashiguchi (Author), Janice A. Frederick (Author), Josef E. Fischer (Author)
Format: Book
Published: Hindawi Limited, 1992-01-01T00:00:00Z.
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3rd Floor Main Library

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