Trypanosoma brucei TbIF1 inhibits the essential F1-ATPase in the infectious form of the parasite.

• 主要な著者: Brian Panicucci (著者), Ondřej Gahura (著者), Alena Zíková (著者)
• フォーマット: 図書
• 出版事項: Public Library of Science (PLoS), 2017-04-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

The mitochondrial (mt) FoF1-ATP synthase of the digenetic parasite, Trypanosoma brucei, generates ATP during the insect procyclic form (PF), but becomes a perpetual consumer of ATP in the mammalian bloodstream form (BF), which lacks a canonical respiratory chain. This unconventional dependence on Fo...