Effects of atrovastatin on concentrations of 3-hydroxy-3-methylglutaryl-coenzyme A- reductase (HMG-CoA-R), proprotein convertase subtilisin/kexin type 9 (PCSK9) and sortilin in patients with type 2 diabetes mellitus and pre-diabetics

• Main Authors: Ali Nosrati Andevari (Author), Soheila Moein (Author), Durdi Qujeq (Author), Zoleikha Moazezi (Author), Karimollah Hajian Tilaki (Author)
• Format: Book
• Published: Society of Diabetic Nephropathy Prevention, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Atorvastatin hinders cardiovascular disease by reducing cholesterol levels. Proprotein convertase subtilisin/kexin type 9 (PCSK9) enhances the secretion of insulin by binding to LDL receptor. Sortilin is committed in the transfer of intracellular proteins through the plasma membrane. O...