Derivatives of 9-phosphorylated acridine as butyrylcholinesterase inhibitors with antioxidant activity and the ability to inhibit β-amyloid self-aggregation: potential therapeutic agents for Alzheimer's disease

We investigated the inhibitory activities of novel 9-phosphoryl-9,10-dihydroacridines and 9-phosphorylacridines against acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and carboxylesterase (CES). We also studied the abilities of the new compounds to interfere with the self-aggregation of...

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主要な著者: Galina F. Makhaeva (著者), Nadezhda V. Kovaleva (著者), Elena V. Rudakova (著者), Natalia P. Boltneva (著者), Sofya V. Lushchekina (著者), Tatiana Yu Astakhova (著者), Elena N. Timokhina (著者), Olga G. Serebryakova (著者), Alexander V. Shchepochkin (著者), Maxim A. Averkov (著者), Irina A. Utepova (著者), Nadezhda S. Demina (著者), Eugene V. Radchenko (著者), Vladimir A. Palyulin (著者), Vladimir P. Fisenko (著者), Sergey O. Bachurin (著者), Oleg N. Chupakhin (著者), Valery N. Charushin (著者), Rudy J. Richardson (著者)
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出版事項: Frontiers Media S.A., 2023-08-01T00:00:00Z.
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