A Pilot Single Cell Analysis of the Zebrafish Embryo Cellular Responses to Uropathogenic Escherichia coli Infection

• Main Authors: Ashley Rawson (Author), Vijay Saxena (Author), Hongyu Gao (Author), Jenaya Hooks (Author), Xiaoling Xuei (Author), Patrick McGuire (Author), Takashi Hato (Author), David Hains (Author), Ryan Anderson (Author), Andrew Schwaderer (Author)
• Format: Book
• Published: Case Western Reserve University, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Uropathogenic Escherichia coli (UPEC) infections are common and when they disseminate can be of high morbidity. Methods: We studied the effects of UPEC infection using single cell RNA sequencing (scRNAseq) in zebrafish. Bulk RNA sequencing has historically been used to evaluate gene expr...