Triptriolide Alleviates Lipopolysaccharide-Induced Liver Injury by Nrf2 and NF-κB Signaling Pathways

• Main Authors: Yi-Qi Yang (Author), Xiao-Teng Yan (Author), Kai Wang (Author), Rui-Min Tian (Author), Zhao-Yu Lu (Author), Li-Lan Wu (Author), Hong-Tao Xu (Author), Yun-Shan Wu (Author), Xu-Sheng Liu (Author), Wei Mao (Author), Peng Xu (Author), Bo Liu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nrf2 (Nuclear Factor Erythroid 2 Related Factor 2) transcription factor not only regulates oxidative stress response, but also represses inflammation by regulating cytokines production and cross-talking with NF-κB signaling pathways. Nrf2 plays an essential role in liver injury induced by oxidative...