Ethanol-Induced Oxidative Stress Modifies Inflammation and Angiogenesis Biomarkers in Retinal Pigment Epithelial Cells (ARPE-19): Role of CYP2E1 and its Inhibition by Antioxidants

• Main Authors: Natalia Martinez-Gil (Author), Lorena Vidal-Gil (Author), Miguel Flores-Bellver (Author), Rosa Maisto (Author), Javier Sancho-Pelluz (Author), Manuel Diaz-Llopis (Author), Jorge M. Barcia (Author), Francisco J. Romero (Author)
• Format: Book
• Published: MDPI AG, 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The retinal pigment epithelium (RPE) plays a key role in retinal health, being essential for the protection against reactive oxygen species (ROS). Nevertheless, excessive oxidative stress can induce RPE dysfunction, promoting visual loss. Our aim is to clarify the possible implication of CYP2E1 in e...