2-Mercaptobenzimidazole clubbed hydrazone for Alzheimer's therapy: In vitro, kinetic, in silico, and in vivo potentials

• Main Authors: Farida Begum (Author), Najeeb Ur Rehman (Author), Ajmal Khan (Author), Sajid Iqbal (Author), Rehan Zafar Paracha (Author), Jalal Uddin (Author), Ahmed Al-Harrasi (Author), Muhammad Arif Lodhi (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Alzheimer's is a type of dementia that affects the affected person's thinking, memory, and behavior. It is a multifactorial disease, developed by the breakdown of the neurotransmitter acetylcholine via acetylcholinesterase (AChE). The present study was designed to evaluate potential inhibi...