Validation of a Double-Sandwich Enzyme-Linked Immunoassay for Pharmacokinetic Study of an rh-aFGF Hydrogel in Rat Skin and Serum

• Main Authors: Qi Hui (Author), Rongshuai Yang (Author), Chao Lu (Author), Jianing Bi (Author), Lijia Li (Author), Jianxiang Gong (Author), Li Zhang (Author), Zi Jin (Author), Xiaokun Li (Author), Xiaojie Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In this study, we validated a double-sandwich enzyme-linked immunosorbent assay (ELISA) to investigate the pharmacokinetics of a recombinant human acidic fibroblast growth factor (rh-aFGF) hydrogel in rat skin and serum. A total of 130 Sprague-Dawley rats were divided into a control group, rh-aFGF h...