Dynamic Editome of Zebrafish under Aminoglycosides Treatment and Its Potential Involvement in Ototoxicity

• Main Authors: Sijia Yan (Author), Yulan Lu (Author), Lin He (Author), Xinzhi Zhao (Author), Lihua Wu (Author), Huizhong Zhu (Author), Menglin Jiang (Author), Yu Su (Author), Wei Cao (Author), Weidong Tian (Author), Qinghe Xing (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

RNA editing is an important co- and post-transcriptional event that generates RNA and protein diversity. Aminoglycosides are a group of bactericidal antibiotics and a mainstay of antimicrobial therapy for several life-threatening infections. However, aminoglycosides can induce ototoxicity, resulting...