Is There an Opportunity for Current Chemotherapeutics to Up-regulate MIC-A/B Ligands?

Natural killer (NK) cells are critical effectors of the immune system. NK cells recognize unhealthy cells by specific ligands [e.g., MHC- class I chain related protein A or B (MIC-A/B)] for further elimination by cytotoxicity. Paradoxically, cancer cells down-regulate MIC-A/B and evade NK cell'...

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Main Authors: Kendel Quirk (Author), Shanmugasundaram Ganapathy-Kanniappan (Author)
Format: Book
Published: Frontiers Media S.A., 2017-10-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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