lncRNA HOTTIP Recruits EZH2 to Inhibit PTEN Expression and Participates in IM Resistance in Chronic Myeloid Leukemia

• Glavni autori: Jing Liu (Autor), Lin Yang (Autor), Xiaojun Liu (Autor), Lu Liu (Autor), Menghan Liu (Autor), Xuefeng Feng (Autor), Jianmin Luo (Autor)
• Format: Knjiga
• Izdano: Hindawi Limited, 2022-01-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Objective. To investigate that HOTTIP suppressed PTEN gene expression and was involved in IM resistance in chronic myeloid leukemia through recruitment of EZH2 protein. Methods. Seventy-one cases of bone marrow monocytes diagnosed with CML in the Second Hospital of Hebei Medical University from 2018...