HIV-1 is Transported into the Central Nervous System by Trafficking Infected Cells

• Main Authors: Laura Kincer (Author), Gretja Schnell (Author), Ronald Swanstrom (Author), Melissa Miller (Author), Serena Spudich (Author), Joseph Eron (Author), Richard Price (Author), Sarah Joseph (Author)
• Format: Book
• Published: Case Western Reserve University, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: In this work, we carried out a cross-sectional study examining HIV-1 and HCV free virus concentrations in blood and cerebrospinal fluid (CSF) to determine whether HIV-1 enters the central nervous system (CNS) passively as virus particles or in the context of migrating infected cells. If...