The Development of Super-Saturated Rebamipide Eye Drops for Enhanced Solubility, Stability, Patient Compliance, and Bioavailability

• Main Authors: Dong-Jin Jang (Author), Jun Hak Lee (Author), Da Hun Kim (Author), Jin-Woo Kim (Author), Tae-Sung Koo (Author), Kwan Hyung Cho (Author)
• 格式: 圖書
• 出版: MDPI AG, 2023-03-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

The present study aimed to develop clear aqueous rebamipide (REB) eye drops to enhance solubility, stability, patient compliance, and bioavailability. For the preparation of a super-saturated 1.5% REB solution, the pH-modification method using NaOH and a hydrophilic polymer was employed. Low-viscosi...