Metabolomics-based discovery of XHP as a CYP3A4 inhibitor against pancreatic cancer

• Main Authors: Yuting Yang (Author), Yanlei Guo (Author), Hua Luo (Author), Menglei Wang (Author), Fang Chen (Author), Huawei Cui (Author), Ping Chen (Author), Zhujun Yin (Author), Li Li (Author), Ying Dai (Author), Jin Zeng (Author), Junning Zhao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Xihuang Wan (XHW), a purgative and detoxifying agent, is commonly utilized in modern medicine as a treatment and adjuvant therapy for various malignancies, including breast cancer, liver cancer, and lung cancer. A clinical study demonstrated the potential usefulness of the combination of...