Folic Acid-Functionalized Metal-Organic Framework Nanoparticles as Drug Carriers Improved Bufalin Antitumor Activity Against Breast Cancer

• Main Authors: Hairong Zeng (Author), Chao Xia (Author), Bei Zhao (Author), Mengmeng Zhu (Author), HaoYue Zhang (Author), Die Zhang (Author), Xin Rui (Author), Huili Li (Author), Yi Yuan (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Bufalin (Buf), an active ingredient of the traditional Chinese medicine Chansu, is known to have anticancer effects for breast cancer. However, its poor solubility, high toxicity, and extensive side effects limit its use. Metal-organic frameworks (MOFs) are a class of promising drug delivery systems...