Comparative effects of incretin-based therapy on doxorubicin-induced nephrotoxicity in rats: the role of SIRT1/Nrf2/NF-κB/TNF-α signaling pathways

• 主要な著者: Sandy R. Botros (著者), Asmaa I. Matouk (著者), Amr Amin (著者), Gehan H. Heeba (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2024-02-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Introduction: Nephrotoxicity represents a major complication of using doxorubicin (DOX) in the management of several types of cancers. Increased oxidative stress and the activation of inflammatory mediators play outstanding roles in the development of DOX-induced kidney damage. This study aimed to i...