High tumor cell platelet‐derived growth factor receptor beta expression is associated with shorter survival in malignant pleural epithelioid mesothelioma

• Main Authors: Hely Ollila (Author), Juuso Paajanen (Author), Henrik Wolff (Author), Ilkka Ilonen (Author), Eva Sutinen (Author), Katja Välimäki (Author), Arne Östman (Author), Sisko Anttila (Author), Eeva Kettunen (Author), Jari Räsänen (Author), Olli Kallioniemi (Author), Marjukka Myllärniemi (Author), Mikko I Mäyränpää (Author), Teijo Pellinen (Author)
• Format: Book
• Published: Wiley, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Malignant pleural mesothelioma (MPM) has a rich stromal component containing mesenchymal fibroblasts. However, the properties and interplay of MPM tumor cells and their surrounding stromal fibroblasts are poorly characterized. Our objective was to spatially profile known mesenchymal markers...