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The Glutaminase-1 Inhibitor [<sup>11</sup>C-carbony]BPTES: Synthesis and Positron Emission Tomography Study in Mice

Bis-2-(5-phenylacetamido-1,3,4-thiadiazol-2-yl)ethyl sulfide (BPTES) is a selective inhibitor of glutaminase-1 (GLS1), consequently inhibiting glutaminolysis. BPTES is known for its potent antitumor activity and plays a significant role in senescent cell removal. In this study, we synthesized [<s...

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Main Authors:	Yiding Zhang (Author), Katsushi Kumata (Author), Lin Xie (Author), Yusuke Kurihara (Author), Masanao Ogawa (Author), Tomomi Kokufuta (Author), Nobuki Nengaki (Author), Ming-Rong Zhang (Author)
Format:	Book
Published:	MDPI AG, 2023-07-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
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