Potent Quinoline-Containing Combretastatin A-4 Analogues: Design, Synthesis, Antiproliferative, and Anti-Tubulin Activity
A novel series of quinoline derivatives of combretastatin A-4 incorporating rigid hydrazone and a cyclic oxadiazole linkers were synthesized and have demonstrated potent tubulin polymerization inhibitory properties. Many of these novel derivatives have shown significant antiproliferative activities...
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Main Authors: | , , , , , , , , |
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Format: | Book |
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MDPI AG,
2020-11-01T00:00:00Z.
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Internet
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A1234.567 |
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Copy 1 | Available |