Potent Quinoline-Containing Combretastatin A-4 Analogues: Design, Synthesis, Antiproliferative, and Anti-Tubulin Activity

A novel series of quinoline derivatives of combretastatin A-4 incorporating rigid hydrazone and a cyclic oxadiazole linkers were synthesized and have demonstrated potent tubulin polymerization inhibitory properties. Many of these novel derivatives have shown significant antiproliferative activities...

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Main Authors: Tarek S. Ibrahim (Author), Mohamed M. Hawwas (Author), Azizah M. Malebari (Author), Ehab S. Taher (Author), Abdelsattar M. Omar (Author), Niamh M. O'Boyle (Author), Eavan McLoughlin (Author), Zakaria K. Abdel-Samii (Author), Yaseen A. M. M. Elshaier (Author)
Format: Book
Published: MDPI AG, 2020-11-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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