Efficient synthesis, biological evaluation, and docking study of isatin based derivatives as caspase inhibitors

In this paper, a new series of isatin-sulphonamide based derivatives were designed, synthesised and evaluated as caspase inhibitors. The compounds containing 1-(pyrrolidinyl)sulphonyl and 2-(phenoxymethyl)pyrrolidin-1-yl)sulphonyl substitution at C5 position of isatin core exhibited better results c...

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Main Authors: Loghman Firoozpour (Author), Lixin Gao (Author), Setareh Moghimi (Author), Parvin Pasalar (Author), Jamshid Davoodi (Author), Ming-Wei Wang (Author), Zahra Rezaei (Author), Armin Dadgar (Author), Hoda Yahyavi (Author), Massoud Amanlou (Author), Alireza Foroumadi (Author)
Format: Book
Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
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Call Number: A1234.567
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