Targeting Anion Exchange of Osteoclast, a New Strategy for Preventing Wear Particles Induced- Osteolysis

• Main Authors: Chuanlong Wu (Author), Xuqiang Liu (Author), Ruixin Sun (Author), Yunhao Qin (Author), Zhiqing Liu (Author), Shengbing Yang (Author), Tingting Tang (Author), Zhenan Zhu (Author), Degang Yu (Author), Fengxiang Liu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Joint replacement is essential for the treatment of serious joint disease. However, prosthetic failure remains an important clinical issue, with periprosthesis osteolysis (PO), caused by osteoclastic bone resorption induced by wear particles, being the leading cause of failure. Nuclear factor of act...