Functional loss of inactive rhomboid-like protein 2 mitigates obesity by suppressing pro-inflammatory macrophage activation-triggered adipose inflammation

• Main Authors: Minxuan Xu (Author), Chenxu Ge (Author), Yuting Qin (Author), Deshuai Lou (Author), Qiang Li (Author), Jing Feng (Author), Yekuan Wu (Author), Linfeng Hu (Author), Bochu Wang (Author), Jun Tan (Author)
• Format: Book
• Published: Elsevier, 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Chronic inflammation of adipose tissues contributes to obesity-triggered insulin resistance. Unfortunately, the potential molecular mechanisms regarding obesity-associated systemic inflammation and metabolic disorder remain complicated. Here, we report that inactive rhomboid-like protein...