Functional loss of inactive rhomboid-like protein 2 mitigates obesity by suppressing pro-inflammatory macrophage activation-triggered adipose inflammation

• Egile Nagusiak: Minxuan Xu (Egilea), Chenxu Ge (Egilea), Yuting Qin (Egilea), Deshuai Lou (Egilea), Qiang Li (Egilea), Jing Feng (Egilea), Yekuan Wu (Egilea), Linfeng Hu (Egilea), Bochu Wang (Egilea), Jun Tan (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2020-04-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Objective: Chronic inflammation of adipose tissues contributes to obesity-triggered insulin resistance. Unfortunately, the potential molecular mechanisms regarding obesity-associated systemic inflammation and metabolic disorder remain complicated. Here, we report that inactive rhomboid-like protein...