Challenges in drug discovery for thiazolidinedione substitute
Thiazolidinedione (TZD) is a powerful insulin sensitizer in the treatment of type 2 diabetes. It acts as a ligand to the nuclear receptor PPARγ (peroxisome proliferator-activated receptor-gamma) and induces transcription of PPARγ-responsive genes. TZD controls lipid synthesis and storage in adipose...
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| Format: | Book |
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Elsevier,
2011-10-01T00:00:00Z.
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Internet
Connect to this object online.3rd Floor Main Library
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A1234.567 |
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