Crisaborole Inhibits Itch and Pain by Preventing Neutrophil Infiltration in a Mouse Model of Atopic Dermatitis

• Main Authors: Darya Pavlenko (Author), Zeynep Todurga Seven (Author), Lauren Bystrom (Author), Anika Markan (Author), Rebecca Verpile (Author), Hirotake Ishida (Author), Tasuku Akiyama (Author)
• Format: Book
• Published: Medical Journals Sweden, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Crisaborole, a phosphodiesterase 4 (PDE4) inhibitor, has been approved for the treatment of mild to moderate atopic dermatitis. Atopic dermatitis is often associated with increased pain. Using a mouse model, this study investigated whether crisaborole suppresses pain associated with atopic dermatiti...