Inhibiting NLRP3 Inflammasome Activation by CY-09 Helps to Restore Cerebral Glucose Metabolism in 3×Tg-AD Mice

• Hoofdauteurs: Shuangxue Han (Auteur), Zhijun He (Auteur), Xia Hu (Auteur), Xiaoqian Li (Auteur), Kaixin Zheng (Auteur), Yingying Huang (Auteur), Peng Xiao (Auteur), Qingguo Xie (Auteur), Jiazuan Ni (Auteur), Qiong Liu (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2023-03-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

The reduction of the cerebral glucose metabolism is closely related to the activation of the NOD-like receptor protein 3 (NLRP3) inflammasome in Alzheimer's disease (AD); however, its underlying mechanism remains unclear. In this paper, ¹⁸F-flurodeoxyglucose positron emis...