Anti-psoriatic effects of Honokiol through the inhibition of NF-κB and VEGFR-2 in animal model of K14-VEGF transgenic mouse

• Main Authors: Jiaolin Wen (Author), Xianhuo Wang (Author), Heying Pei (Author), Caifeng Xie (Author), Neng Qiu (Author), Shucai Li (Author), Wenwen Wang (Author), Xia Cheng (Author), Lijuan Chen (Author)
• Format: Book
• Published: Elsevier, 2015-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Honokiol (HK), a biphenolic neolignan isolated from Magnolia officinalis, has been reported to possess anti-inflammatory and anti-angiogenic activaties. In this study, our aim was to investigate anti-psoriatic activities of HK and the involved mechanisms. In vitro, the effects of HK on the regulatio...