Two Types of Cation Channel Activated by Stimulation of Muscarinic Receptors in Guinea-Pig Urinary Bladder Smooth Muscle

• Main Authors: Masayuki Yamamoto (Author), Toshihiro Unno (Author), Hayato Matsuyama (Author), Masanobu Kohda (Author), Noriyuki Masuda (Author), Masakazu Nishimura (Author), Toshiaki Ishii (Author), Seiichi Komori (Author)
• Format: Book
• Published: Elsevier, 2008-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The present study, aiming to elucidate ion channel mechanisms underlying muscarinic receptor-induced depolarization, has characterized membrane currents induced by carbachol in single guinea-pig urinary bladder myocytes. Application of carbachol to cells that were voltage-clamped at − 50 mV produced...