Translational Studies on Anti-Atrial Fibrillatory Action of Oseltamivir by its in vivo and in vitro Electropharmacological Analyses

• Main Authors: Ryuichi Kambayashi (Author), Hiroko Izumi-Nakaseko (Author), Ai Goto (Author), Kazuya Tsurudome (Author), Hironori Ohshiro (Author), Taku Izumi (Author), Mihoko Hagiwara-Nagasawa (Author), Koki Chiba (Author), Ryota Nishiyama (Author), Satomi Oyama (Author), Yoshio Nunoi (Author), Yoshinori Takei (Author), Akio Matsumoto (Author), Atsushi Sugiyama (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Oseltamivir has been shown to prolong the atrial conduction time and effective refractory period, and to suppress the onset of burst pacing-induced atrial fibrillation in vitro. To better predict its potential clinical benefit as an anti-atrial fibrillatory drug, we performed translational studies b...