Columbianadin Dampens In Vitro Inflammatory Actions and Inhibits Liver Injury via Inhibition of NF-κB/MAPKs: Impacts on ^∙OH Radicals and HO-1 Expression

• Main Authors: Thanasekaran Jayakumar (Author), Shaw-Min Hou (Author), Chao-Chien Chang (Author), Tsorng-Harn Fong (Author), Chih-Wei Hsia (Author), Yen-Jen Chen (Author), Wei-Chieh Huang (Author), Periyakali Saravanabhavan (Author), Manjunath Manubolu (Author), Joen-Rong Sheu (Author), Chih-Hsuan Hsia (Author)
• Format: Book
• Published: MDPI AG, 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Columbianadin (CBN), a natural coumarin isolated from <i>Angelica decursiva,</i> is reported to have numerous biological activities, including anticancer and platelet aggregation inhibiting properties. Here, we investigated CBN's anti-inflammatory effect in lipopolysaccharide (LPS)-...